Search results for " Protein A chromatography"
Article
Improving Process-Scale Chromatography
The new affinity resins work for new antibody types, smaller antibody fragments, and fusion proteins where Protein A chromatography will not because they bind other portions of IgGs. “Affinity resins …
Article
Making the Move to Continuous Chromatography
Making the Move to Continuous Chromatography
Early adopters are benefiting from lower costs and increased productivity.
By Cynthia A. Challener
Tashatuvango/Shu…
Article
A Look at the Affinity Chromatography Landscape
A Look at the Affinity Chromatography Landscape
New ligands are being developed to meet the separation and purification needs of next-gen biologics.
By Cynthia A. Challener
…
Article
Process Chromatography: Continuous Optimization
…obal product marketing manager for Cytiva, are typically purified using a platform approach in which protein A chromatography resins are used in the first capture step. Polishing is then achieved usi…
Article
Process Chromatography Selection for Downstream Processing Applications
Chromatography considerations
BioPharm: What are some alternatives to Protein A chromatography?
Becerra-Arteaga (MilliporeSigma): It is challenging to compete with a technology able to provide…
Article
HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
If used correctly, these new analytical methods can reduce analysis and product development time.
ABSTRACT
Monoclonal antibodies represent a significant portion of sales in the biopharma…
Article
Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
Increasing upstream titers can make the Protein A chromatography process step the rate-limiting step in downstream purification. Protein A chromatography columns are frequently too large, limiting the…
Article
Improvements in Protein A Chromatography
Bolton recently published a paper “Role of more than 40 years of improvement in Protein A chromatography in the growth of the therapeutic antibody industry,” and also presented at the spring ACS meeti…
Article
Innovative Chromatography Resins Can Improve Purity and Quality
Meanwhile, an innovation such as a fiber-based protein A chromatography resin offers advantages over traditional resins. “Until recently, chromatography based on different porous bead formats has been…
Article
Technology Innovations Improve Process Chromatography Performance
As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.
By Feliza Mirasol
Selecting an appropriate separation technology fo…